Alnylam Pharmaceuticals, Inc.

Cambridge, MA Professional servicesNAICS 541700

Self-funded health planPlan year 2025Renews January
1,833Participants+3% vs. prior year
$4.3MEst. pharmacy spend / yrParticipants × national avg.
Jan 2027Next renewalPlan year begins January 1
#8 of 39Professional services in MABy participants

Overview

Alnylam Pharmaceuticals, Inc. sponsors a self-funded health plan that covered 1,833 participants in plan year 2025, up 3% from the prior year. The plan year starts in January. Alongside medical, its benefits filing reports life insurance, dental, vision, short-term disability, and more.

Plan type
ERISA welfare benefit plan, self-funded (benefits paid from employer assets or a trust)
Participants
1,833 · prior year 1,780
Plan year
Begins January 1 · next renewal January 2027
Health plans filed
Alnylam Pharmaceuticals, Inc. Consolidated Welfare Benefits Plan, plan 501 (1,833 participants)
Broker compensation
$151K across insured contracts
MedicalLife insuranceDentalVisionShort-term disabilityLong-term disabilityDeath benefitsOther welfare benefits

Insurance carriers

Insured coverage reported on Schedule A. Self-funded medical claims aren't reported there.

CarrierCoverageCoveredPremiumBroker comp
Prudential Insurance Company of AmericaLife, Long-term disability1,821$1.3M$81K
Eyemed Vision Care on Behalf of Fidelity Security Life Insurance Co.Vision4,038$358K$47K
National Union Fire Ins. Co. of Pittsburgh, PABusiness Travel Accident1,780$94K$24K
CuralincEmployee Assistance Program1,100$20K—

Pharmacy benefit estimate

StreamRX estimate for a plan this size. Not based on this plan's claims.

$4.3M/ year

Estimated prescription spend: 1,833 participants × $2,371 national average per member. Usually higher once dependents are counted.

$113K–$279K/ year

Typical savings opportunity found in independent reviews of plans this size.

Brands with a generic available$33K–$83K
Lower-cost therapeutic alternatives$48K–$101K
Generic pricing vs. actual cost$21K–$63K
PBM contract terms$11K–$33K
The DOL's PBM fee disclosure rule first applies to this plan for the plan year beginning January 2028: semiannual PBM compensation reports and an annual audit right.

Form 5500 filing details

Filing
Form 5500 with Schedule A, plan year 2025
Plan sponsor
Alnylam Pharmaceuticals, Inc.
Sponsor EIN
04-3696884
Plan number
501
Filed with
U.S. Department of Labor (EBSA) via EFAST2

Verify this filing: search EIN 04-3696884 in the Department of Labor's EFAST2 Form 5500 search.

Retirement plan

Plan
Alnylam Pharmaceuticals, Inc. Savings & Investment Plan
Type
401(k) plan
Participants
2,624

About this data

Source: Alnylam Pharmaceuticals, Inc.'s Form 5500 filing for plan year 2025 and its Schedule A insurance reports, published by the U.S. Department of Labor. "Self-funded" means the filing reports benefits paid from employer assets or a trust, with no medical insurance contract or with a stop-loss contract. Pharmacy figures are StreamRX estimates based on national averages. StreamRX is not affiliated with Alnylam Pharmaceuticals, Inc..

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